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A DISPOSABLE OPTICAL BIOSENSOR BASED ON TOTAL INTERNAL REFLECTION FLUORESCENCE
Sutherland, R. Frevert, J. Place, J. F. Knoell, H. Bregnard, A. Dähne, C. Revillet, G. Hybl, E.
Sutherland, R.
Frevert, J.
Place, J. F.
Knoell, H.
Bregnard, A.
Dähne, C.
Revillet, G.
Hybl, E.
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Issue Date
1987
Submitted date
2023-09-06
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Abstract
A novel disposable biosensor device is described, based on the generation
of evanescent light waves at an optical interface. The sensor is
injection moulded from high optical quality plastic and consists of
two parts, the waveguide and a cuvette for containing the sample solution.
Antigens are attached to the waveguide surface and the reaction
with antibodies is monitored by exciting and collecting fluorescent
light "back-tunneled" out of the waveguide. A model assay for human
IgG is used to demonstrate that this biosensor can give rapid, sensitive
results.
Citation
Biosensors International Workshop 1987, 305 - 306
DOI
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Type
Book chapter
conference paper
conference paper
Language
en
Description
Series/Report no.
GBF Monographs, Volume 10
ISSN
0930-4320
EISSN
ISBN
0-89573-683-7
3-527-26801-4
3-527-26801-4
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Attribution-NonCommercial-ShareAlike 4.0 International