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Successful Fecal Microbiota Transplantation in a Patient with Severe Complicated Clostridium difficile Infection after Liver Transplantation.
Schneider, Kai Markus Wirtz, Theresa H Kroy, Daniela Albers, Stefanie Neumann, Ulf Peter Strowig, Till Sellge, Gernot Trautwein, Christian
Schneider, Kai Markus
Wirtz, Theresa H
Kroy, Daniela
Albers, Stefanie
Neumann, Ulf Peter
Strowig, Till
Sellge, Gernot
Trautwein, Christian
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Issue Date
2018-05-18
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Abstract
Clostridium difficile infection (CDI) represents one of the most common healthcare-associated infections. Due to increasing numbers of recurrences and therapy failures, CDI has become a major disease burden. Studies have shown that fecal microbiota transplantation (FMT) can both be a safe and highly efficacious therapy for patients with therapy-refractory CDI. However, patients undergoing solid organ transplantation are at high risk for CDI due to long-term immunosuppression, previous antibiotic therapy, and proton pump inhibitor use. Additionally, these patients may be especially prone to adverse events related to FMT. Here, we report a successful FMT in a patient with severe therapy-refractory CDI after liver transplantation.
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Successful Fecal Microbiota Transplantation in a Patient with Severe Complicated Clostridium difficile Infection after Liver Transplantation., 12 (1):76-84 Case Rep Gastroenterol
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en
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1662-0631