Zainuddin, Elmi NMentel, RenateWray, VictorJansen, RolfNimtz, ManfredLalk, MichaelMundt, Sabine2008-05-062008-05-062007-07Cyclic depsipeptides, ichthyopeptins A and B, from Microcystis ichthyoblabe. 2007, 70 (7):1084-8 J. Nat. Prod.0163-38641760258610.1021/np060303shttp://hdl.handle.net/10033/24872Bioassay-guided isolation of antiviral compounds from the cultured cyanobacterium Microcystis ichthyoblabe provided two novel cyclic depsipeptides, ichthyopeptins A (1) and B (2). Their structures were determined by 1D (1H and 13C) and 2D (COSY, TOCSY, ROESY, HMQC, and HMBC) NMR spectra, ESIMS-MS, and amino acid analysis. The fraction containing both cyclic depsipeptides exhibited antiviral activity against influenza A virus with an IC50 value of 12.5 microg/mL.enAntiviral AgentsDepsipeptidesGermanyInfluenza A virusInhibitory Concentration 50MicrocystisMolecular StructureNuclear Magnetic Resonance, BiomolecularArticleJournal of natural products